Vimentin Polyclonal Antibody, 100ul[BT-AP09528] Centrifuges Mutations resulting in haploinsufficiency for

Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2)

and inflammation

Alternatively spliced transcript variants encoding different isoforms have been noted for this gene

This family member is most abundant in muscle but is expressed in all tissues

Vimentin Polyclonal Antibody, 100ul[BT-AP09528] Centrifuges Mutations resulting in haploinsufficiency forVIM encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. Vimentin encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low density lipoprotein (LDL) derived cholesterol from a lysosome to the