DSG4 Polyclonal Antibody, 50ul Cell Culture Plates A highly conserved region of

A highly conserved region of approximately 150 aa

Alternately spliced transcript variants have been observed for this gene

|tissue specificity:Expressed in monocytes and mature macrophages such as Kupffer cells in the liver| red pulp macrophages in the spleen| cortical macrophages in the thymus| resident bone marrow macrophages and meningeal macrophages of the central nervous system

such as the conversion of 2

DSG4 Polyclonal Antibody, 50ul Cell Culture Plates A highly conserved region ofThis gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.