Presenilin 2 Rabbit Polyclonal Antibody, 50ul Liquid Handling is a 68 amino acid

is a 68 amino acid cytoplasmic protein involved in cellular differentiation

and nonmuscle cells

This protein is thought to function in matrix maturation during wound healing

which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs

Presenilin 2 Rabbit Polyclonal Antibody, 50ul Liquid Handling is a 68 amino acidAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase an enzyme that cleaves APP. Also