c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 20ul Purification Contains 1 SH3 domain

Contains 1 SH3 domain

and commonly used as a molecular tag to study protein localization

Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs

This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 20ul Purification Contains 1 SH3 domainThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a