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Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos PEAK1 (pseudopodium enriched atypical kinase

SKU: 52095199067

4.2
USD162.00 USD196.00

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Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos PEAK1 (pseudopodium enriched atypical kinaseThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

PEAK1 (pseudopodium enriched atypical kinase 1) encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family

|tissue specificity:Expressed in skeletal muscle

Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex

This protease

Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos PEAK1 (pseudopodium enriched atypical kinaseThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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