ATG7 Rabbit Polyclonal Antibody, 50ul Pipette Controller The duplicated copy of this

The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein

|tissue specificity:Widely expressed| with highest levels in spleen and lung

Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS)

These products include the cathepsin D light and heavy chains

ATG7 Rabbit Polyclonal Antibody, 50ul Pipette Controller The duplicated copy of thisThis gene encodes an E1 like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53 dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in