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DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizes

SKU: 52383829241

4.4
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DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizesNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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Description

In rat| this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal

colon and lung

alternatively spliced form

and fetal kidney

DHX58 Polyclonal Antibody, 50ul Cellular Function Assays In rat| this protein localizesNegative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58 mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,Belongs to the helicase family.,Contains 1 helicase ATP binding domain.,Contains 1 helicase C terminal domain.,subunit: Interacts with DDX58 and probably blocks its homomultimerization.,

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