Dvl-2 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging DEFA4 differs from other genes

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

and thought to prevent premature exposure of developing fetal tissues to adult levels of thyroid hormones

Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0)

which mediates membrane targeting by binding to phosphatidylinositol 3

Dvl-2 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging DEFA4 differs from other genesDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved