ALKB2 Polyclonal Antibody, 100ul Gene Synthesis Mutations in this gene result

Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB)

Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354

This gene encodes a member of the sirtuin family of proteins| homologs to the yeast Sir2 protein

Two alternatively spliced variants encoding distinct isoform

ALKB2 Polyclonal Antibody, 100ul Gene Synthesis Mutations in this gene resultThe Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1 methyladenine and 3 methylcytosine (Duncan et al., 2002