Pim-1 Polyclonal Antibody, 20ul Pathway and Network Analysis Knockout studies in mice suggest

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor)

NXF3 (nuclear RNA export factor 3) is one member of a family of nuclear RNA export factor genes

MRPL39 (mitochondrial ribosomal protein L39) encodes a 39S subunit protein

Pim-1 Polyclonal Antibody, 20ul Pathway and Network Analysis Knockout studies in mice suggestThe protein encoded by PIM1 (Pim 1 proto oncogene, serine threonine kinase) belongs to the Ser Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both