TAB2(Phospho-Ser372) Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Some granins have been shown

Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones

The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression

These two variants encode the same isoform

The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis

TAB2(Phospho-Ser372) Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Some granins have been shownThe protein encoded by this gene is an activator of MAP3K7 TAK1 which is required for for the IL 1 induced activation of nuclear factor kappaB and MAPK8 JNK. This protein forms a kinase complex with TRAF6 MAP3K7 and TAB1 and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein along with TAB1 and MAP3K7 also participates in the signal transduction induced by TNFSF11 RANKl through the activation of the receptor activator of NF kappaB