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Phospho-AIP4 (Y420) Polyclonal Antibody, 50ul Metabolic enzymes tool compounds TBX10 encodes a member of

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Phospho-AIP4 (Y420) Polyclonal Antibody, 50ul Metabolic enzymes tool compounds TBX10 encodes a member ofITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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Description

TBX10 encodes a member of the T-box family of transcription factors

A similar murine protein interacts with TNFR-associated factor 1 (TRAF1)| TNFR-associated factor 2 (TRAF2)| and cylindromatosis

Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia

metabolism

Phospho-AIP4 (Y420) Polyclonal Antibody, 50ul Metabolic enzymes tool compounds TBX10 encodes a member ofITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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