HECW1 Polyclonal Antibody, 20ul Serum It forms a signaling receptor

It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand

LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV)

This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication

It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta

HECW1 Polyclonal Antibody, 20ul Serum It forms a signaling receptorE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW