IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis with multiple epiphyseal dysplasia

with multiple epiphyseal dysplasia

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Promotes neuritogenesis in developing hippocampal neurons

Three alternatively spliced transcript variants encoding the same protein have been described for CPM

IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis with multiple epiphyseal dysplasiaNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell