BubR1 Polyclonal Antibody, 100ul 3D Culture Two alternatively spliced transcripts encoding

Two alternatively spliced transcripts encoding the same isoform have been reported

not all variants have been described

This gene encodes a member of the nuclear hormone receptor family

These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins

BubR1 Polyclonal Antibody, 100ul 3D Culture Two alternatively spliced transcripts encodingBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.