Histone H3 Monoclonal Antibody(1G1), 100ul Endonucleases & Exonucleases • Passed rigorous explosion-proof test

• Passed rigorous explosion-proof test

disease:A chromosomal aberration involving FOXO4 is found in acute leukemias

so this may be a tumor suppressor gene

This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane

Histone H3 Monoclonal Antibody(1G1), 100ul Endonucleases & Exonucleases • Passed rigorous explosion-proof testHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin