IL-16 Polyclonal Antibody, 100ul[BT-AP04446] Antibody Development Ligand binding causes a conformation

Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors

The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex

This cytokine has overlapping signaling functions with TNF

The first two N-terminal amino acids can be cleaved from human CCL4 by CD26/DPPIV

IL-16 Polyclonal Antibody, 100ul[BT-AP04446] Antibody Development Ligand binding causes a conformationThe protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C terminal peptide, while the N terminal product may play a