KLOT Polyclonal Antibody, 100ul Aspirating Pipets Polyribonucleotide nucleotidyltransferase 1 encoded by

Polyribonucleotide nucleotidyltransferase 1 encoded by PNPT1 elongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation

and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region

encodes over 1

The encoded enzyme catalyzes the sulfation of the proteoglycan keratin

KLOT Polyclonal Antibody, 100ul Aspirating Pipets Polyribonucleotide nucleotidyltransferase 1 encoded byThis gene encodes a type I membrane protein that is related to beta glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e. g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.