Hrs Polyclonal Antibody, 50ul[BT-AP04215] Metabolic enzymes It is a component of

It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

share a 5' non-coding exon

cell-cell signaling

Hrs Polyclonal Antibody, 50ul[BT-AP04215] Metabolic enzymes It is a component ofHepatocyte growth factor regulated tyrosine kinase substrate encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.