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Nephrocystin-5 Polyclonal Antibody, 100ul Hepatocytes Expression of this gene stimulated

SKU: 55841834458

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Nephrocystin-5 Polyclonal Antibody, 100ul Hepatocytes Expression of this gene stimulatedIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin binding motif containing protein 1 has a central coiled coil region and two calmodulin binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin binding motif containing protein 1 is thought to play a role in ciliary function. Defects

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Description

Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid

The encoded protein may function as a tumor suppressor

and also as a coactivator of NF-kappaB-mediated transcription

CDK8 and CDC2L6/CDK11

Nephrocystin-5 Polyclonal Antibody, 100ul Hepatocytes Expression of this gene stimulatedIQCB1 encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQ calmodulin binding motif containing protein 1 has a central coiled coil region and two calmodulin binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQ calmodulin binding motif containing protein 1 is thought to play a role in ciliary function. Defects

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