KDM5B Polyclonal Antibody, 20ul Lysosome GO annotations related to this

GO annotations related to this gene include pyruvate transmembrane transporter activity

Also phosphorylated on Ser-524 independently of reelin signaling

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression

KDM5B Polyclonal Antibody, 20ul Lysosome GO annotations related to thisThis gene encodes a lysine specific histone demethylase that belongs to the jumonji ARID domain containing family of histone demethylases. The encoded protein is capable of demethylating tri , di and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair.