eEF2K Polyclonal Antibody, 50ul[BT-AP02841] Pathway and Network Analysis The encoded protein acts as

The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions

2002 [PubMed 12191433])

alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms

Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I

eEF2K Polyclonal Antibody, 50ul[BT-AP02841] Pathway and Network Analysis The encoded protein acts asEEF2K encodes a highly conserved protein kinase in the calmodulin mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti cancer treatment.