SOX21 Polyclonal Antibody, 20ul Pasteur Pipets Mutations in this gene caused

Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4)

Various mutations have been described for this gene and have been linked to human diseases

Alternate splicing results in both coding and non-coding variants of this gene

encode negative regulators of Rho GTPases (see ARHA

SOX21 Polyclonal Antibody, 20ul Pasteur Pipets Mutations in this gene causedSRY related HMG box (SOX) genes encode a family of DNA binding proteins containing a 79 amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).