Histone H2A Polyclonal Antibody, 50ul[BT-AP03999] Protein Post-translational Modification Promotes MEK and RAF phosphorylation

Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane

Beta tryptases appear to be the main isoenzymes expressed in mast cells

Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation

Histone H2A Polyclonal Antibody, 50ul[BT-AP03999] Protein Post-translational Modification Promotes MEK and RAF phosphorylationHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.