PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates SIM1 transcript was detected only

SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested

This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4

but down regulated in ovarian cancer cell lines and primary carcinomas

Caspases exist as inactive proenzymes composed of a prodomain| a large protease subunit| and a small protease subunit

PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates SIM1 transcript was detected onlyThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment