SC65 Polyclonal Antibody, 20ul Low-speed Centrifuges Expression of SERPINB7 is upregulated

Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

It interacts in a complex with chromatin modifying factors

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades

Pentraxin 3 promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation

SC65 Polyclonal Antibody, 20ul Low-speed Centrifuges Expression of SERPINB7 is upregulatedThis nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.