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Rat Mothers Against Decapentaplegic Homolog 4, SMAD4 ELISA Kit, 96T sgRNA Oligos Blocks anoikis of malignant kidney

SKU: 57050563798

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Rat Mothers Against Decapentaplegic Homolog 4, SMAD4 ELISA Kit, 96T sgRNA Oligos Blocks anoikis of malignant kidneyCommon SMAD (co SMAD) is the coactivator and mediator of signal transduction by TGF beta (transforming growth factor). Component of the heterotrimeric SMAD2 SMAD3 SMAD4 complex that forms in the nucleus and is required for the TGF mediated signaling. Promotes binding of the SMAD2 SMAD4 FAST 1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3 SMAD4 JUN FOS

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Description

Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2 (PubMed: 18957423)

reverse triiodothyronine (rT3) and diidothyronine (T2)

PubMed: 25242865)

these tips are DNase/RNase-free

Rat Mothers Against Decapentaplegic Homolog 4, SMAD4 ELISA Kit, 96T sgRNA Oligos Blocks anoikis of malignant kidneyCommon SMAD (co SMAD) is the coactivator and mediator of signal transduction by TGF beta (transforming growth factor). Component of the heterotrimeric SMAD2 SMAD3 SMAD4 complex that forms in the nucleus and is required for the TGF mediated signaling. Promotes binding of the SMAD2 SMAD4 FAST 1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3 SMAD4 JUN FOS

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