Slit3 Polyclonal Antibody, 20ul Cellular Function Assays Mutations in CDKN1C are implicated

Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome

Alternatively spliced transcript variants encoding distinct isoforms have been found

This protein has a sequence similarity to yeast Prp17 protein

Alternatively spliced transcript variants encoding distinct isoforms have been reported

Slit3 Polyclonal Antibody, 20ul Cellular Function Assays Mutations in CDKN1C are implicatedThe protein encoded by SLIT3 (slit guidance ligand 3) is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for SLIT3.