ANGP4 Polyclonal Antibody, 50ul Cell fragmentation and collection This protein lacks the metalloproteinase

This protein lacks the metalloproteinase and disintegrin-like domains

and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult

It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues

It contains a 5' CpG island that may be a frequent target of hypermethylation| and it may undergo hypermethylation-based silencing in some bladder cancers

ANGP4 Polyclonal Antibody, 50ul Cell fragmentation and collection This protein lacks the metalloproteinaseAngiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell specific tyrosine protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin.