Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research PTM:Several N-termini have been identified
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Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research PTM:Several N-termini have been identifiedMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.
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