Phospho-Caldesmon (S789) Polyclonal Antibody, 50ul Immunoassays Alternative splicing of this gene

Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms

The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain

This rearrangement produces the p80HT gene which encodes for a truncated 80 kDa protein (p80HT)

PTM:Phosphorylated by LYN

Phospho-Caldesmon (S789) Polyclonal Antibody, 50ul Immunoassays Alternative splicing of this geneCALD1 encodes a calmodulin and actin binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+) calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+) dependent inhibition of