Human 4-hydroxynonenal, 4HNE ELISA Kit, 96T| Sensitivity: 5.23ng/L | Range: 10 - 2000ng/L Culture Tubes Mutations in PMS1 cause hereditary

Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype

Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41'

The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins

Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior (PubMed: 28280205

Human 4-hydroxynonenal, 4HNE ELISA Kit, 96T| Sensitivity: 5.23ng/L | Range: 10 - 2000ng/L Culture Tubes Mutations in PMS1 cause hereditary