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p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma of which the most well-characterized

SKU: 59430096515

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USD185.00 USD216.00

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p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma of which the most well-characterizedThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

of which the most well-characterized category is represented by the HOX genes

As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme

The encoded protein has six putative transmembrane segments (S1-S6)

enhancing the DNA-binding activity of serum response factor

p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma of which the most well-characterizedThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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