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Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology MDK encodes a member of

SKU: 59496338653

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Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology MDK encodes a member ofBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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Description

MDK encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid

This protein is not restricted to leukemic cells

where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene

Knockout studies in mice suggest that the different receptors

Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology MDK encodes a member ofBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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