Cathepsin B Polyclonal Antibody, 100ul[BT-AP01235] Vacuum Filter This gene is expressed in

This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia

Mutations in this gene or some other NER components result in Xeroderma pigmentosum| a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age

Plays a role in axon guidance

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

Cathepsin B Polyclonal Antibody, 100ul[BT-AP01235] Vacuum Filter This gene is expressed inCTSB encodes a member of the C1 family of peptidases. Alternative splicing of CTSB results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and