SOX21 Polyclonal Antibody, 100ul Organelle Studies DM plays a central role

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

May function as a negative regulator of axonal growth

also known as Best macular dystrophy

The protein is thought to play a role in cell-cell recognition during development of the central nervous system

SOX21 Polyclonal Antibody, 100ul Organelle Studies DM plays a central roleSRY related HMG box (SOX) genes encode a family of DNA binding proteins containing a 79 amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).