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HBA Polyclonal Antibody, 50ul Protein Expression APIP is an APAF1 (MIM

SKU: 59944976158

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HBA Polyclonal Antibody, 50ul Protein Expression APIP is an APAF1 (MIMThe human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha 1 alpha 2 alpha 1 theta 3'. The alpha 2 (HBA2) and alpha 1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult

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Description

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al

The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1

At the nucleoplasmic side of the NPC

PTM:Phosphorylated on cytoplasmic tyrosine residues

HBA Polyclonal Antibody, 50ul Protein Expression APIP is an APAF1 (MIMThe human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5' zeta pseudozeta mu pseudoalpha 1 alpha 2 alpha 1 theta 3'. The alpha 2 (HBA2) and alpha 1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult

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