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ZAP-70(Phospho Tyr292) Polyclonal Antibody, 50ul Miscellaneous This gene is closely linked

SKU: 60150106250

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ZAP-70(Phospho Tyr292) Polyclonal Antibody, 50ul Miscellaneous This gene is closely linkedThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene

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Description

This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13

including the hexadecapeptide

with lower levels in the prostate

Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al

ZAP-70(Phospho Tyr292) Polyclonal Antibody, 50ul Miscellaneous This gene is closely linkedThis gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T cell antigen receptor (TCR) stimulation, functions in the initial step of TCR mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene

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