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N2DL3 Polyclonal Antibody, 20ul Variant Libraries CYB561D2 (Cytochrome b561 domain-containing protein

SKU: 60158842023

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N2DL3 Polyclonal Antibody, 20ul Variant Libraries CYB561D2 (Cytochrome b561 domain-containing proteinThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.

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Description

CYB561D2 (Cytochrome b561 domain-containing protein 2)

MIM 612725) (Stefansson and Brautigan| 2006

Among its related pathways are Regulation of Microtubule Cytoskeleton

The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization

N2DL3 Polyclonal Antibody, 20ul Variant Libraries CYB561D2 (Cytochrome b561 domain-containing proteinThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.

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