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CD59 Polyclonal Antibody, 20ul[BT-AP01752] Glassware Sets differentiation from the proB cell

SKU: 60359037987

4.4
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CD59 Polyclonal Antibody, 20ul[BT-AP01752] Glassware Sets differentiation from the proB cellApoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12 DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced

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Description

differentiation from the proB cell to the preB cell stage

These proteins facilitate signal transduction as components of several multiprotein complexes

An important paralog of this gene is TXNDC12

ANKRD30A is a differentiation antigen and a potential target for antibody‐based therapies in breast cancers

CD59 Polyclonal Antibody, 20ul[BT-AP01752] Glassware Sets differentiation from the proB cellApoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12 DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced

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