NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles It has also been implicated

It has also been implicated in the progression of several cancers

which may play a role in the differentiation of tendon cells and spinal cord interneurons

Two alternative transcripts encoding different proteins have been described

The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy

NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles It has also been implicatedThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several