HECW1 Polyclonal Antibody, 50ul Antibodies Paraspeckles may function in the

Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development

that dimerize to form the active enzyme

This enzyme can act as a sphingolipid delta(4)-desaturase| and also as a sphingolipid C4-hydroxylase

HECW1 Polyclonal Antibody, 50ul Antibodies Paraspeckles may function in theE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW