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NR0B2 Polyclonal Antibody, 20ul Miscellaneous DES encodes a muscle-specific class

SKU: 61391930790

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NR0B2 Polyclonal Antibody, 20ul Miscellaneous DES encodes a muscle-specific classThe protein encoded by this gene is an unusual orphan receptor that contains a putative ligand binding domain but lacks a conventional DNA binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid

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Description

DES encodes a muscle-specific class III intermediate filament

The Ku p70/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold

This enzyme| which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation| functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases| Lck and Fyn

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NR0B2 Polyclonal Antibody, 20ul Miscellaneous DES encodes a muscle-specific classThe protein encoded by this gene is an unusual orphan receptor that contains a putative ligand binding domain but lacks a conventional DNA binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid

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