GDF-9 Polyclonal Antibody, 100ul[BT-AP03536] Sealing Film The product of CRK has

The product of CRK has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways

Such repeats are however not predicted by any detection method

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia

GDF-9 Polyclonal Antibody, 100ul[BT-AP03536] Sealing Film The product of CRK hasGDF9 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. Growth differentiation factor 9 regulates ovarian function. Reduced