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CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences PYCARD encodes an adaptor protein

SKU: 61802534095

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CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences PYCARD encodes an adaptor proteinKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction

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Description

PYCARD encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD)

member RAS oncogene family encoded by RAB40B has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles

and thus it may function in mitosis

Mutations in ACTA1 cause nemaline myopathy type 3

CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences PYCARD encodes an adaptor proteinKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction

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