HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos APP encodes a cell surface

APP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides

improving the stability of the structure

and a C-terminal hydrophobic region

This gene is intronless and the encoded protein is secreted

HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 20ul Diagnostic Probes & Oligos APP encodes a cell surfaceThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different