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Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer thymus and colon

SKU: 62644229039

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Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer thymus and colonThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

thymus and colon

also named as CK1

Involved in neuronal differentiation

Kinases that recognize phosphorylation sites in which the surrounding peptides have an alpha-helical conformation

Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer thymus and colonThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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