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Glucuronidase Beta Polyclonal Antibody, 100ul Cell Culture Plates The Mediator complex links gene-specific

SKU: 63794370958

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Glucuronidase Beta Polyclonal Antibody, 100ul Cell Culture Plates The Mediator complex links gene-specificGUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin 4,6 sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

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Description

The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery

The Ig-like V-type domain 2 mediates interaction with CXADR

forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases

Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5

Glucuronidase Beta Polyclonal Antibody, 100ul Cell Culture Plates The Mediator complex links gene-specificGUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin 4,6 sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

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