GDF-8 Monoclonal Antibody, 100ul Glassware Mutations in this gene are

Mutations in this gene are associated with a lethal skeletal disorder

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The protein encoded by this gene is a uridine kinase

by being activated by cold temperature below 25 degrees Celsius

GDF-8 Monoclonal Antibody, 100ul Glassware Mutations in this gene areThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation