BMP-2 Polyclonal Antibody, 100ul[BT-AP00920] Custom Peptide Synthesis The protein is normally found

The protein is normally found in the membrane of the endoplasmic reticulum

It is associated with CREM and confers a powerful transcriptional activation function

Most Caucasians have two major isozymes

This protein may also function as a repressor of transcription

BMP-2 Polyclonal Antibody, 100ul[BT-AP00920] Custom Peptide Synthesis The protein is normally foundBMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer, which plays a role in bone and cartilage